Country:United States>New York>Shirley
45-1 Ramsey Road, Shirley, NY 11967, USA
Company:Creative-Diagnostics
Mobile:6316197922
Tell1-631-619-7922
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. https://www.creative-diagnostics.com/TRC8-peptide-*-436.htm
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