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Acadesine AICAR Review AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICAR ribonucleotide, ZMP, or Acadesine. AICAR is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P. AICAR is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation. The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels, which, in turn, allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue. These two functions allow for more energy conversion, which helps burn fat and also sustain output in activity. This is what scientists and athletes/bodybuilders are interested in. Acadesine AICAR stack with GW* Both AICAR and Cardarine are on WADA’s banned substances list, and if used together they make a potent endurance stack. One of the differences between the two is that GW* is a PPAR-delta agonist, while AICAR is a PPAR-delta AMPK axis agonist. Acadesine Dosage Dosages range from 150 milligrams (mg) per day (if stacked with GW), up to 500mg a day when used solo. Considering the fact that each bottle typically comes in 50mg dosages, that is quite expensive, as already mentioned above. Economically, it makes most sense to run AICAR during the 4 weeks leading up to your competition.
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